Variant Data Manipulation

Glow offers functionalities to perform genomic variant data ETL, manipulation, and quality control.

• Variant I/O with Spark SQL
  • VCF
  • BGEN
  • PLINK
• Create a Genomics Delta Lake
  • VCF to Delta Lake table notebook
• Variant Quality Control
  • Notebook
• Sample Quality Control
  • Computing user-defined sample QC metrics
• Liftover
  • Create a liftover cluster
  • Coordinate liftover
  • Variant liftover
• Variant Normalization
  • Usage
  • Options
• Split Multiallelic Variants
  • Usage
• Utility Functions
  • Struct transformations
  • Spark ML transformations
  • Variant data transformations